Diffuse Large B-Cell Lymphoma News

News

Early, Late DLBCL Relapse Linked With Distinct Evolutionary Dynamics

08/17/2023

“These observations have implications for clinical trial design and patient management, where early and late relapse patient populations should be considered separately and support additional molecular characterization of tumors at relapse to...

“These observations have...

08/17/2023

First Report Managed Care

News

Zanubrutinib Plus R-CHOP Effective for Non-GCB DLBCL With Extranodal Involvement

08/02/2023

Jolynn Tumolo ;

Researchers studied the efficacy and safety of a combination regimen that included zanubrutinib among treatment-naïve patients with non–germinal center B cell–like (non-GCB) diffuse large B-cell lymphoma (DLBCL) with multiple extranodal...

Researchers studied the efficacy...

08/02/2023

First Report Managed Care

News

Study Finds Low Rate of CAR T-cell Therapy in Older Adults With DLBCL

07/27/2023

Jolynn Tumolo ;

"CAR T-cell therapy was associated with favorable effectiveness, but the CAR T-cell therapy use in older patients was very low," particularly among patients aged at least 75 years, according to researchers.

"CAR T-cell therapy was...

07/27/2023

First Report Managed Care

News

CNS Prophylaxis Shows Limited Effectiveness in Preventing CNS Relapse in DLBCL

07/21/2023

Jolynn Tumolo ;

In addition to effectiveness, researchers also evaluated the financial toxicity and side effects associated with CNS prophylaxis for patients with diffuse large B-cell lymphoma.

In addition to effectiveness,...

07/21/2023

First Report Managed Care

News

Prognosis Worse for Patients With DLBCL and Mental Health Disorders

07/20/2023

Julie Gould ;

Among patients with diffuse large B-cell lymphoma, pre-existing depression and anxiety were both associated with worse prognoses, according to recent findings.

Among patients with diffuse...

07/20/2023

First Report Managed Care

News

Epcoritamab Shows Durable Response in Relapsed/Refractory Large B-Cell Lymphoma

07/14/2023

Jolynn Tumolo ;

“The observed high response rates with durability in patients with refractory large B-cell lymphoma treated with epcoritamab, including postchimeric antigen receptor-T therapy, represent further evidence of the value of bispecific antibodies...

“The observed high response...

07/14/2023

First Report Managed Care

News

05/12/2023

Jordan Kadish ;

According to findings from a phase 3 trial, biosimilar rituximab had comparable efficacy and safety to originator rituximab among patients with diffuse large B-cell lymphoma.

According to findings from a...

05/12/2023

Oncology

News

Anti-CD19 Monoclonal Antibodies for Treating Patients With R/R DLBCL

05/20/2022

Maria Asimopoulos ;

Researchers reviewed loncastuximab tesirine and tafasitamab for treating patients with relapsed or refractory diffuse large B-cell lymphoma.

Researchers reviewed...

05/20/2022

First Report Managed Care

News

Loncastuximab Tesirine Efficacious, Safe for Patients With R/R DLBCL

05/13/2022

Jolynn Tumolo ;

Study authors assessed the efficacy of loncastuximab tesirine in treating patients with relapsed or refractory diffuse large B-cell lymphoma.

Study authors assessed the...

05/13/2022

First Report Managed Care

News

HRQoL Maintained or Improved With Treatment for Patients With R/R DLBCL

04/25/2022

Jolynn Tumolo ;

An antibody-drug conjugate already shown to have antitumor activity and manageable toxicity also improved health-related quality of life in patients with relapsed/refractory diffuse large B-cell lymphoma, according to new findings.

An antibody-drug conjugate...

04/25/2022

First Report Managed Care

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Patient-Reported Outcomes Similarly Impacted By Migraine Treatments

05/17/2019

Researchers recently found that patient-reported outcomes (PROs) were no different among patients treated with calcitonin gene-related peptide (CGRP) antagonists or onabotulinumtoxinA (ONA) for the indication of chronic migraine prophylaxis.

Researchers recently found that...

05/17/2019

First Report Managed Care

News

Cancer`s growing burden: the high cost of care

03/02/2012

First Report Managed Care

Mergers Pave Way for Good Opportunity to Enter Medicare Advantage Market

11/06/2015

While the largest insurance companies await their fate at the hands of federal regulators, other plans and investors should pay close attention to the opportunity to acquire divested plans from the two deals.

While the largest insurance...

11/06/2015

First Report Managed Care

News

Trial to Test CAR T-Cell Therapy for Refractory Progressive MS

03/18/2024

Jolynn Tumolo ;

An autologous, fully human CD19 chimeric antigen receptor (CAR) T-cell product candidate recently received clearance from the US Food and Drug Administration (FDA) as an investigational new drug for the treatment of patients with refractory...

An autologous, fully human CD19...

03/18/2024

First Report Managed Care

News

Cost-Effective Treatment Option for Tremor-Dominant Parkinson Disease

10/13/2020

Magnetic resonance-guided focused ultrasound thalamotomy is more cost-effective than continued medical therapy for patients with tremor-dominant Parkinson disease.

Magnetic resonance-guided...

10/13/2020

First Report Managed Care

Video Insights

Videos

Bridging the Gaps in Prior Authorization: Challenges, Solutions, and Collaboration for Better Patient Care

11/13/2024

David Sand, MD, MBA, chief medical officer at ZeOmega, discusses the challenges of prior authorization, emphasizing the need for transparency, evidence-based standards, collaboration between payers and providers, and the potential for...

David Sand, MD, MBA, chief...

11/13/2024

First Report Managed Care

Videos

The Evolving Role of CGRP-targeting Therapies in Migraine Prevention

10/31/2024

Richard Lipton, MD, provides insights on the American Headache Society’s position statement update on calcitonin gene-related peptide (CGRP)-targeting therapies as a first-line option for the prevention of migraine.

Richard Lipton, MD, provides...

10/31/2024

First Report Managed Care

Videos

Unmet Needs in the Treatment and Management of Non–Small Cell Lung Cancer

09/26/2024

Alexander Spira , MD, PhD;

Alexander I. Spira, MD, PhD, discusses significant unmet needs in the treatment and management of non–small cell lung cancer (NSCLC).

Alexander I. Spira, MD, PhD,...

09/26/2024

First Report Managed Care

Videos

Treatment Options for NSCLC: A Discussion on Coverage, Clinical Outcomes, and Payer Perspectives

09/25/2024

Learn about research developments in 1L therapy for NSCLC patients with EGFR mutations and how outcomes may impact coverage and reimbursement decisions for insurers.

Learn about research...

09/25/2024

First Report Managed Care

Videos

Addressing the Root Cause of a Common Ocular Condition: A Virtual Roundtable

09/04/2024

View a roundtable discussion on Demodex blepharitis, a prevalent ocular condition that often goes undiagnosed in patients.

View a roundtable discussion on...

09/04/2024

First Report Managed Care

Videos

Addressing Health Disparities and Promoting Equity: The Role of Advanced Imaging Solutions

08/15/2024

Guest expert Jordan Bazinsky discusses the challenges facing the medical imaging industry, the potential of AI and emerging technologies, the role of advanced imaging solutions in promoting health equity, and the key trends and challenges...

Guest expert Jordan Bazinsky...

08/15/2024

First Report Managed Care

Videos

Promising Therapies and Clinical Trials for Chronic Lymphocytic Leukemia

08/14/2024

Farrukh T. Awan , MD;

Farrukh Awan, MD, highlights promising therapies and clinical trials within the field of chronic lymphocytic leukemia (CLL).

Farrukh Awan, MD, highlights...

08/14/2024

Journal of Clinical Pathways

Videos

Evolving Health Care Contact Centers Into Drivers of Value-Based Care

07/31/2024

Discover how health care contact centers can transform into drivers of value-based care through AI, automation, upskilling agents, and rethinking workflows and metrics to improve patient outcomes and population health.

Discover how health care contact...

07/31/2024

First Report Managed Care

Videos

Enhancing Patient Medication Adherence: Insights and Strategies From Asembia 2024

06/11/2024

Lucille Accetta, PharmD, MBA, MSPH, Senior Vice President of CVS Specialty Operations

Key stakeholders in the health care industry gathered to discuss prevalent topics at this year's Asembia annual summit. Medication adherence emerged as one of the most talked-about issues. In a session led by Lucille Accetta, PharmD, MBA,...

Key stakeholders in the health...

06/11/2024

First Report Managed Care

Melissa Andel, Principal, CommonHealth Solutions, LLC

Videos

Navigating the Impact of the Inflation Reduction Act: Implications for Payers, Patients, and Manufacturers

05/24/2024

Melissa Andel, Principal, CommonHealth Solutions, LLC

Learn about the impacts of the Inflation Reduction Act on payers and patients, highlighting the changes in Medicare benefits and drug coverage coming in 2025 and 2026.

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